Endocrine Abstracts

Introduction: Adequate hormone replacement therapy in adrenal insufficiency (AI) is essential. Patients should have basic knowledge about their condition and how to minimise the change on an adrenal crisis. Education on how and when hydrocortisone replacement therapy should be adjusted together with instruction and practice an emergency injection are considered important measures to prevent a crisis. A nurse-led group-based education programme (GEP) was developed, and given fr...

Background: To avoid the serious complications of diabetes glucose control must be tackled aggressively in type 2 diabetes. However some patients with type 2 diabetes are severely insulin resistant and although they are treated with large doses of insulin their blood glucose is still not optimally controlled.Aim: This project aims to determine the dose–response to insulin in patients with type 2 diabetes and severe insulin resistance.<p class="a...

Introduction: Adequate hormone replacement therapy in adrenal insufficiency is essential. Patients should have basic knowledge about their condition and what to do in situations which could trigger an adrenal crisis. Education on how and when hydrocortisone replacement therapy should be adjusted as well as instruction and practice an emergency injection are considered important measures to prevent an adrenal crisis. A standardized nurse-led group-based education programme (GEP...

Background: Polycystic ovary syndrome (PCOS) is associated with obesity and increased risk of type 2 diabetes mellitus.Aim: The aim of the present prospective cohort study was to investigate possible associations between PCOS and obstetric outcomes in 199 Danish women with PCOS and 995 controls and to describe the impact of different PCOS phenotypes on the risk of adverse obstetric outcomes.Methods: Women diagnosed with PCOS at Ode...

Introduction: Adolescents spend much time using blue-light emitting screen devices such as smartphones, tablets and computers. Blue light affects the central circadian clock in the suprachiasmatic nucleus (SCN) as well as melatonin secretion by the pineal gland. Screen use in adolescents strongly associates with reduced sleep quality and sleep duration. However, there is a lack of intervention studies that reduce blue light exposure due to screen use in adolescents.<p clas...

IntroductionObesity is highly prevalent, comes with serious health burden and is difficult to treat. In a minority, there is a genetic cause for the obesity. In these patients, therapy-resistant obesity is often observed despite intensive lifestyle treatment. Moreover, it is still unclear whether bariatric surgery is less successful in genetic obesity. Liraglutide is a Glucagon-Like-Peptide-1 (GLP-1) receptor agonist or GLP-1 analogue, showing positive e...